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Image Search Results
Journal: bioRxiv
Article Title: Advancing (-)-Premarineosin A as a Potent Antimalarial Therapeutic via Metabolic Engineering and Late-Stage Derivatization
doi: 10.1101/2025.01.28.635342
Figure Lengend Snippet: Compounds were tested against 3D7 (chloroquine-sensitive) and Dd2 (chloroquine-resistant) P. falciparum strains for antimalarial activity and the HEK293 embryonic kidney and MOLT4 T-cell leukemia cell lines for cytotoxicity to mammalian cells. Selectivity Index (SI) = EC50 Mammalian Cell Line / EC50 P. falciparum .
Article Snippet: Cells were obtained from the following sources:
Techniques: Activity Assay